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Article

Paramutation in Drosophila Requires Both Nuclear and Cytoplasmic Actors of the piRNA Pathway and Induces Cis-spreading of piRNA Production.

Genetics - 1 Dec 2015

Hermant Catherine, Boivin Antoine, Teysset Laure, Delmarre Valérie, Asif-Laidin Amna, van den Beek Marius, Antoniewski Christophe, Ronsseray Stéphane

Abstract excerpt

Transposable element activity is repressed in the germline in animals by PIWI-interacting RNAs (piRNAs), a class of small RNAs produced by genomic loci mostly composed of TE sequences. The mechanism of induction of piRNA production by these loci is still enigmatic. We have shown that, in Drosophila melanogaster, a cluster of tandemly repeated P-lacZ-white transgenes can be activated for piRNA production by...

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Identifiers

PMID: 26482790
DOI: 10.1534/genetics.115.180307
PMCID: PMC4676525

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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