Genomic inbreeding coefficients based on the distribution of the length of runs of homozygosity in a closed line of Iberian pigs.

doi:10.1186/s12711-015-0153-1

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Article

Genomic inbreeding coefficients based on the distribution of the length of runs of homozygosity in a closed line of Iberian pigs.

Genetics, selection, evolution : GSE - 16 Oct 2015

Gomez-Raya Luis, Rodríguez Carmen, Barragán Carmen, Silió Luis

Abstract excerpt

BACKGROUND: The increasing availability of DNA markers provides new metrics of inbreeding based on single nucleotide polymorphisms (SNPs), i.e. molecular inbreeding or the proportion of runs of homozygosity (ROH), as alternatives to traditional pedigree-based inbreeding coefficients. However, none of these metrics incorporate the length of ROH as an indicator of recent inbreeding. Novel inbreeding coefficients...

Topics

Algorithms
Animals
Chromosomes, Mammalian
Homozygote
Inbreeding
Pedigree
Polymorphism, Single Nucleotide
Swine

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Identifiers

PMID: 26475049
DOI: 10.1186/s12711-015-0153-1
PMCID: PMC4608316

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