Article

Lynch Syndrome: Current Status of CRC in Biotechnological and Biomedical Fields

2021-08-12

Abstract excerpt

Lynch syndrome (LS) is an autosomal dominant genetic condition caused by mutations in the DNA mismatch repair (MMR) genes in the germline. Colorectal cancer and/or LS-associated cancer are more likely in people who carry pathogenic mutations in these genes. Cancers of the endometrium, small intestine, stomach, pancreas, and biliary tract, ovarian, brain, upper urinary tract, and skin are among the cancer types lin...

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Literature Corpus work: b9c46eb3-e2c7-54bd-9aed-b35809338188
DOI: 10.20944/preprints202107.0303.v2

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