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Article

Development of novel real-time PCR methodology for quantification of COL11A1 mRNA variants and evaluation in breast cancer tissue specimens.

BMC cancer - 14 Oct 2015

Karaglani Makrina, Toumpoulis Ioannis, Goutas Nikolaos, Poumpouridou Nikoleta, Vlachodimitropoulos Dimitrios, Vasilaros Spyridon, Rizos Ioannis, Kroupis Christos

Abstract excerpt

BACKGROUND: Collagen XI is a key structural component of the extracellular matrix and consists of three alpha chains. One of these chains, the α1 (XI), is encoded by the COL11A1 gene and is transcribed to four different variants at least (A, B, C and E) that differ in the propensity to N-terminal domain proteolysis and potentially in the way the extracellular matrix is arranged. This could affect the ability of...

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Identifiers

PMID: 26466668
DOI: 10.1186/s12885-015-1725-8
PMCID: PMC4606509

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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