Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations Between the T280M and V249I SNPs in CX3CR1 and the Risk of Age-Related Macular Degeneration.

Investigative ophthalmology & visual science - 1 Aug 2015

Zhang Rui, Wang Li-Yuan, Wang Ya-Feng, Wu Chang-Rui, Lei Chun-Ling, Wang Ming-Xu, Ma Le

Abstract excerpt

PURPOSE: Two common single nucleotide polymorphisms (SNPs) in the CX3CR1 gene, T280M and V249I, have been reported to affect the risk of age-related macular degeneration (AMD) in several studies. The aim of the present study was to combine all published data on the relationship between these two variants and AMD susceptibility in a meta-analysis to clarify this association. METHODS: MEDLINE, EMBASE, and ISI Web...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to CX3C Chemokine Receptor 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Linkage Disequilibrium

Share to Macular Degeneration

Share to Polymorphism, Single Nucleotide

Share to Receptors, Chemokine

Source

Identifiers

PMID: 26305531
DOI: 10.1167/iovs.15-16830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations Between the T280M and V249I SNPs in CX3CR1 and the Risk of Age-Related Macular Degeneration.PMID 26305531Read ↗

Association of CX3CR1 (V249I and T280M) polymorphisms with age-related macular degeneration: a meta-analysis.Semantic proximity Read ↗

Prospective study of common variants in CX3CR1 and risk of macular degeneration: pooled analysis from 5 long-term studies.Semantic proximity Read ↗

CX3CR1 polymorphisms and the risk of age-related macular degeneration.Semantic proximity Read ↗

The involvement of sequence variation and expression of CX3CR1 in the pathogenesis of age-related macular degeneration.Semantic proximity Read ↗

No association between the T280M polymorphism of the CX3CR1 gene and exudative AMD.Semantic proximity Read ↗

Association of sequence variation in the CX3CR1 gene with geographic atrophy age-related macular degeneration in a Greek population.Semantic proximity Read ↗

Study of Polymorphisms in CX3CR1, PLEKHA1 and VEGF genes as risk factors for age-related macular degeneration in Indian patients.Semantic proximity Read ↗

Nonsynonymous single nucleotide polymorphisms in the complement component 3 gene are associated with risk of age-related macular degeneration: a meta-analysis.Semantic proximity Read ↗

Polymorphisms in Selected Genes and Their Association with Age-Related Macular Degeneration in a Chinese Population.Semantic proximity Read ↗

Association of polymorphisms of complement factor I rs141853578 (G119R) with age-related macular degeneration in Iranian population.Semantic proximity Read ↗

Association between a functional genetic polymorphism (rs2230199) and age-related macular degeneration risk: a meta-analysis.Semantic proximity Read ↗

Two polymorphisms in the Fractalkine receptor CX3CR1 gene influence the development of atherosclerosis: a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.