Is the Hodgkin cell a T- or B-lymphocyte? Recent evidence from geno- and immunophenotypic analysis and in-vitro cell lines.

doi:10.1002/hon.2900070202

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Article

Is the Hodgkin cell a T- or B-lymphocyte? Recent evidence from geno- and immunophenotypic analysis and in-vitro cell lines.

Hematological oncology - 1 Jan 2000

Drexler H G, Jones D B, Diehl V, Minowada J

Abstract excerpt

The cellular derivation of Hodgkin (H) and Reed-Sternberg (RS) cells remains a controversial issue. A large body of conflicting results in the literature led to a variety of discordant speculations. The application of immunophenotyping, molecular biology and tissue culture provided additional mea...

Topics

B-Lymphocytes
Gene Rearrangement
Genes, Immunoglobulin
Genotype
Hodgkin Disease
Humans
Phenotype
T-Lymphocytes
Tumor Cells, Cultured

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