Recent insights into the biology of Hodgkin lymphoma: unraveling the mysteries of the Reed-Sternberg cell.

doi:10.1586/14737159.7.6.805

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Article

Recent insights into the biology of Hodgkin lymphoma: unraveling the mysteries of the Reed-Sternberg cell.

Expert review of molecular diagnostics - 1 Nov 2007

Roullet Michele R, Bagg Adam

Abstract excerpt

The microscopic pathology of Hodgkin lymphoma has been recognized for well over a century; however, only in the past 15 years has the enigmatic nature of this peculiar neoplasm been somewhat unraveled. This has been accomplished via a combination of the acquisition, via microdissection, of the prototypically rare malignant cells and their subsequent analysis via a variety of modalities, including genomic studies...

Topics

Herpesvirus 4, Human
Hodgkin Disease
Humans
Immune Tolerance
Inflammation
NF-kappa B
Phenotype
Reed-Sternberg Cells
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 18020910
DOI: 10.1586/14737159.7.6.805

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