Article
Validation of Pooled Whole-Genome Re-Sequencing in Arabidopsis lyrata.
PloS one - 1 Jan 2015
Fracassetti Marco, Griffin Philippa C, Willi Yvonne
Abstract excerpt
Sequencing pooled DNA of multiple individuals from a population instead of sequencing individuals separately has become popular due to its cost-effectiveness and simple wet-lab protocol, although some criticism of this approach remains. Here we validated a protocol for pooled whole-genome re-sequencing (Pool-seq) of Arabidopsis lyrata libraries prepared with low amounts of DNA (1.6 ng per individual). The...
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