Article
Validation of SNP allele frequencies determined by pooled next-generation sequencing in natural populations of a non-model plant species.
PloS one - 1 Jan 2013
Rellstab Christian, Zoller Stefan, Tedder Andrew, Gugerli Felix, Fischer Martin C
Abstract excerpt
Sequencing of pooled samples (Pool-Seq) using next-generation sequencing technologies has become increasingly popular, because it represents a rapid and cost-effective method to determine allele frequencies for single nucleotide polymorphisms (SNPs) in population pools. Validation of allele frequencies determined by Pool-Seq has been attempted using an individual genotyping approach, but these studies tend to use...
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