Article
Common sequence polymorphisms shaping genetic diversity in Arabidopsis thaliana.
Science (New York, N.Y.) - 20 Jul 2007
Clark Richard M, Schweikert Gabriele, Toomajian Christopher, Ossowski Stephan, Zeller Georg, Shinn Paul, Warthmann Norman, Hu Tina T, Fu Glenn, Hinds David A, Chen Huaming, Frazer Kelly A, Huson Daniel H, Schölkopf Bernhard, Nordborg Magnus, Rätsch Gunnar, Ecker Joseph R, Weigel Detlef
Abstract excerpt
The genomes of individuals from the same species vary in sequence as a result of different evolutionary processes. To examine the patterns of, and the forces shaping, sequence variation in Arabidopsis thaliana, we performed high-density array resequencing of 20 diverse strains (accessions). More than 1 million nonredundant single-nucleotide polymorphisms (SNPs) were identified at moderate false discovery rates...
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