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Article

Unified tests for fine-scale mapping and identifying sparse high-dimensional sequence associations.

Bioinformatics (Oxford, England) - 1 Feb 2016

Cao Shaolong, Qin Huaizhen, Gossmann Alexej, Deng Hong-Wen, Wang Yu-Ping

Abstract excerpt

MOTIVATION: In searching for genetic variants for complex diseases with deep sequencing data, genomic marker sets of high-dimensional genotypic data and sparse functional variants are quite common. Existing sequence association tests are incapable of identifying such marker sets or individual causal loci, although they appeared powerful to identify small marker sets with dense functional variants. In sequence...

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Identifiers

PMID: 26458888
DOI: 10.1093/bioinformatics/btv586
PMCID: PMC5006306

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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