A weighted U-statistic for genetic association analyses of sequencing data.

Abstract excerpt

With advancements in next-generation sequencing technology, a massive amount of sequencing data is generated, which offers a great opportunity to comprehensively investigate the role of rare variants in the genetic etiology of complex diseases. Nevertheless, the high-dimensional sequencing data poses a great challenge for statistical analysis. The association analyses based on traditional statistical methods...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Angiopoietins
• Share to Genetic Association Studies
• Share to Genetic Variation