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Article

Structural basis of mapping the spontaneous mutations with 5-flurouracil in uracil phosphoribosyltransferase from Mycobacterium tuberculosis.

Biochemical and biophysical research communications - 20 Nov 2015

Ghode Pramila, Jobichen Chacko, Ramachandran Sarath, Bifani Pablo, Sivaraman J

Abstract excerpt

Tuberculosis (TB) remains the second leading cause of death from an infectious disease globally, despite the incessant efforts to control it. Research and development into new TB medicines is imperative for effective TB control; however, new strategies for the rational use of existing drugs, such as through the identification of new drug targets, could also significantly enhance this process. Key enzymes involved...

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Source

Identifiers

PMID: 26456658
DOI: 10.1016/j.bbrc.2015.09.133

Genes

UPRT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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