Article
Increased prevalence of lymphoid tissue inducer cells in the cerebrospinal fluid of patients with early multiple sclerosis.
Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Jul 2016
Degn Matilda, Modvig Signe, Dyring-Andersen Beatrice, Bonefeld Charlotte M, Frederiksen Jette L, Geisler Carsten, von Essen Marina R
Abstract excerpt
BACKGROUND: Inflammatory cytokines produced by cells of the immune system are believed to play a central role in the pathogenesis of multiple sclerosis (MS). Innate lymphoid cells (ILCs) have been shown to produce and secrete a wide range of the cytokines involved in MS pathogenesis; however, a possible implication of ILCs in MS development and disease progression has not been investigated. OBJECTIVE: With this...
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