Article
Association between the CLOCK gene 3111 T > C polymorphism and an irregular menstrual cycle in Korean adolescents.
Journal of psychosomatic obstetrics and gynaecology - 1 Jan 2015
Kim Kye-Hyun, Kim Yunsin, Ha Juwon, Shin Dong-Won, Shin Young-Chul, Oh Kang-Seob, Woo Hee-Yeon, Lim Se-Won
Abstract excerpt
The menstrual cycle is an example of a human infradian rhythm, but an altered sleep-wake cycle or a disrupted circadian rhythm can change the regularity of the menstrual cycle. In this study, we investigated whether an irregular menstrual cycle is associated with polymorphisms in the CLOCK (3111T > C) and/or PER3 (variable number tandem repeat, VNTR) genes, which are known to have an impact on the circadian...
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