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Article

The 3111T/C polymorphism interacts with stressful life events to influence patterns of sleep in females.

Chronobiology international - 1 Aug 2012

Antypa Niki, Mandelli Laura, Nearchou Finiki A, Vaiopoulos Chrysostomos, Stefanis Costas N, Serretti Alessandro, Stefanis Nikos C

Abstract excerpt

Genetic variations in clock-relevant genes have been investigated in relation to sleep abnormalities, both in healthy populations and in mood-disorder patients with inconsistent results. Environmental influences may moderate associations between genes and phenotype. The authors examined the CLOCK 3111T/C polymorphism and several variants within the PER3 gene and their possible interaction with stressful life...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22823872
DOI: 10.3109/07420528.2012.699380

Genes

PER3
CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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