Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell‐specific ablation in the testis: what have we learned?

7 Oct 2015

Abstract excerpt

Testicular development and function is the culmination of a complex process of autocrine, paracrine and endocrine interactions between multiple cell types. Dissecting this has classically involved the use of systemic treatments to perturb endocrine function, or more recently, transgenic models to knockout individual genes. However, targeting genes one at a time does not capture the more wide-ranging role of each...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Sperm and Testicular Function
Share to Testicular diseases and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26446427
DOI: 10.1111/andr.12107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell‐specific ablation in the testis: what have we learned?PMID 26446427Read ↗

Sertoli cell ablation and replacement of the spermatogonial niche in mouseSemantic proximity Read ↗

Good planning and serendipity: exploiting the Cre/Lox system in the testisSemantic proximity Read ↗

Development and Characterization of Cell-Specific Androgen Receptor Knockout Mice.Semantic proximity Read ↗

Updates in Sertoli Cell-Mediated Signaling During Spermatogenesis and Advances in Restoring Sertoli Cell FunctionSemantic proximity Read ↗

Advanced immunostaining approaches to study early male germ cell developmentSemantic proximity Read ↗

Genetics of Mammalian Reproduction: Modeling the End of the GermlineSemantic proximity Read ↗

A novel Amh -Treck transgenic mouse line allows toxin-dependent loss of supporting cells in gonadsSemantic proximity Read ↗

CRISPR/Cas9-based genome editing in mice uncovers 13 testis- or epididymis-enriched genes individually dispensable for male reproduction†Semantic proximity Read ↗

Deconstructing mammalian reproduction: using knockouts to define fertility pathwaysSemantic proximity Read ↗

Sertoli cell as a model in male reproductive toxicology: Advantages and disadvantagesSemantic proximity Read ↗

Identification of Sertoli cell-specific transcripts in the mouse testis and the role of FSH and androgen in the control of Sertoli cell activitySemantic proximity Read ↗

Mixed Signals: Development of the TestisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.