Article
Development and Characterization of Cell-Specific Androgen Receptor Knockout Mice.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
O'Hara Laura, Smith Lee B
Abstract excerpt
Conditional gene targeting has revolutionized molecular genetic analysis of nuclear receptor proteins, however development and analysis of such conditional knockouts is far from simple, with many caveats and pitfalls waiting to snare the novice or unprepared. In this chapter, we describe our experience of generating and analyzing mouse models with conditional ablation of the androgen receptor (AR) from tissues of...
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