Article
Population genetic analysis of Plasmodium knowlesi reveals differential selection and exchange events between Borneo and Peninsular sub-populations.
Scientific reports - 7 Feb 2023
Turkiewicz Anna, Manko Emilia, Oresegun Damiola R, Nolder Debbie, Spadar Anton, Sutherland Colin J, Cox-Singh Janet, Moon Robert W, Lau Yee-Ling, Campino Susana, Clark Taane G
Abstract excerpt
The zoonotic Plasmodium knowlesi parasite is a growing public health concern in Southeast Asia, especially in Malaysia, where elimination of P. falciparum and P. vivax malaria has been the focus of control efforts. Understanding of the genetic diversity of P. knowlesi parasites can provide insights into its evolution, population structure, diagnostics, transmission dynamics, and the emergence of drug resistance....
Topics
- Animals
- Humans
- Genetic Variation
- Plasmodium knowlesi
- Macaca fascicularis
- Malaria
- Malaysia
- Malaria, Vivax
- Malaria, Falciparum
- Genetics, Population
