Population Genomic Structure and Recent Evolution of Plasmodium knowlesi, Peninsular Malaysia.

doi:10.3201/eid2608.190864

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Article

Population Genomic Structure and Recent Evolution of Plasmodium knowlesi, Peninsular Malaysia.

Emerging infectious diseases - 1 Aug 2020

Hocking Suzanne E, Divis Paul C S, Kadir Khamisah A, Singh Balbir, Conway David J

Abstract excerpt

Most malaria in Malaysia is caused by Plasmodium knowlesi parasites through zoonotic infection from macaque reservoir hosts. We obtained genome sequences from 28 clinical infections in Peninsular Malaysia to clarify the emerging parasite population structure and test for evidence of recent adaptation. The parasites all belonged to a major genetic population of P. knowlesi (cluster 3) with high genomewide...

Topics

Animals
Asia
Borneo
Genetic Variation
Malaysia
Metagenomics
Plasmodium knowlesi

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Identifiers

PMID: 32687018
DOI: 10.3201/eid2608.190864
PMCID: PMC7392424

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