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Article

The Pro-Apoptotic Protein Bim Is a MicroRNA Target in Kidney Progenitors

5 May 2011

Abstract excerpt

Understanding the mechanisms that regulate nephron progenitors during kidney development should aid development of therapies for renal failure. MicroRNAs, which modulate gene expression through post-transcriptional repression of specific target mRNAs, contribute to the differentiation of stem cells, but their role in nephrogenesis is incompletely understood. Here, we found that the loss of miRNAs in nephron...

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PMID: 21546576
DOI: 10.1681/asn.2010080841

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