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Article

Ablation of the renal stroma defines its critical role in nephron progenitor and vasculature patterning.

PloS one - 1 Jan 2014

Hum Stephanie, Rymer Christopher, Schaefer Caitlin, Bushnell Daniel, Sims-Lucas Sunder

Abstract excerpt

The renal stroma is an embryonic cell population located in the cortex that provides a structural framework as well as a source of endothelial progenitors for the developing kidney. The exact role of the renal stroma in normal kidney development hasn't been clearly defined. However, previous studies have shown that the genetic deletion of Foxd1, a renal stroma specific gene, leads to severe kidney malformations...

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Identifiers

PMID: 24505489
DOI: 10.1371/journal.pone.0088400
PMCID: PMC3914987

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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