Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity.

PloS one - 1 Jan 2015

Garcia-Etxebarria Koldo, Bracho María Alma, Galán Juan Carlos, Pumarola Tomàs, Castilla Jesús, Ortiz de Lejarazu Raúl, Rodríguez-Dominguez Mario, Quintela Inés, Bonet Núria, Garcia-Garcerà Marc, Domínguez Angela, González-Candelas Fernando, Calafell Francesc

Abstract excerpt

While most patients affected by the influenza A(H1N1) pandemic experienced mild symptoms, a small fraction required hospitalization, often without concomitant factors that could explain such a severe course. We hypothesize that host genetic factors could contribute to aggravate the disease. To test this hypothesis, we compared the allele frequencies of 547,296 genome-wide single nucleotide polymorphisms (SNPs)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Influenza A Virus, H1N1 Subtype

Share to Influenza, Human

Share to Polymorphism, Single Nucleotide

Share to Risk Factors

Share to RNA, Viral

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 26379185
DOI: 10.1371/journal.pone.0135983
PMCID: PMC4574704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

No Major Host Genetic Risk Factor Contributed to A(H1N1)2009 Influenza Severity.PMID 26379185Read ↗

Role of the Host Genetic Susceptibility to 2009 Pandemic Influenza A H1N1.Semantic proximity Read ↗

Host Single Nucleotide Polymorphisms Modulating Influenza A Virus Disease in HumansSemantic proximity Read ↗

Immunogenetic factors associated with severe respiratory illness caused by zoonotic H1N1 and H5N1 influenza viruses.Semantic proximity Read ↗

Host genes and influenza pathogenesis in humans: an emerging paradigm.Semantic proximity Read ↗

The role of polymorphisms in host immune genes in determining the severity of respiratory illness caused by pandemic H1N1 influenza.Semantic proximity Read ↗

An updated systematic review of the role of host genetics in susceptibility to influenza.Semantic proximity Read ↗

Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9).Semantic proximity Read ↗

A functional variation in CD55 increases the severity of 2009 pandemic H1N1 influenza A virus infection.Semantic proximity Read ↗

Association of the host genetic factors, hypercholesterolemia and diabetes with mild influenza in an Iranian population.Semantic proximity Read ↗

Causal relationship between blood traits and severe influenza A(H1N1)pdm09 infection in East Asian: A Mendelian randomization study.Semantic proximity Read ↗

Genetic variants associated with severe pneumonia in A/H1N1 influenza infection.Semantic proximity Read ↗

Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.