Article
Prevalence of CCR5-Δ32 and CCR2-V64I polymorphisms in a mixed population from northeastern Brazil.
Genetics and molecular research : GMR - 2 Oct 2015
Ferreira-Fernandes H, Santos A C C, Motta F J N, Canalle R, Yoshioka F K N, Burbano R R, Rey J A, da Silva B B, Pinto G R
Abstract excerpt
Chemokines are low-molecular weight proteins that play a key role in inflammatory processes. Genomic variations in chemokine receptors are associated with the susceptibility to various diseases. Polymorphisms in chemokine receptor type 5 (CCR5)-Δ32 and CCR2-V64I are related to human immunodeficiency virus infection resistance, which has led to genetic association studies for several other diseases. Given the...
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