Article
Allelic distribution of CCR5 and CCR2 genes in an Italian population sample.
AIDS research and human retroviruses - 20 Jan 2000
Romano-Spica V, Ianni A, Arzani D, Cattarini L, Majore S, Dean M
Abstract excerpt
Genetic polymorphisms of CCR5 and CCR2 human chemokine receptors have been associated with resistance during HIV-1 infection and disease progression. The protective effect of mutant alleles at these loci has important implications in AIDS pathogenesis. Chemokine receptors have a role in viral entry into target cells as well as in immune response modulation. In the present report, we studied the frequency of...
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