Article
The effect of combined polymorphisms in chemokines and chemokine receptors on the clinical course of HIV-1 infection in a Brazilian population.
Memorias do Instituto Oswaldo Cruz - 1 Jun 2011
Vieira Valdimara Corrêa, Barral Maria Fernanda Martínez, Mendoza-Sassi Raul Andrés, Silveira Jussara Maria, Soares Marcelo Alves, de Martínez Ana Maria Barral
Abstract excerpt
Polymorphisms in genes that encode chemokines or their receptors can modulate susceptibility to human immunodeficiency virus (HIV) infection and disease progression. The objective of this study was to assess the frequency of polymorphisms CCR5-Δ32, CCR2-64I, CCR5-59029A and SDF1-3'A and their role in the course of HIV infection in a Southern Brazilian population. Clinical data were obtained from 249 patients for...
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