Article
Production of bioactive chitosan oligosaccharides using the hypertransglycosylating chitinase-D from Serratia proteamaculans.
Bioresource technology - 1 Dec 2015
Madhuprakash Jogi, El Gueddari Nour Eddine, Moerschbacher Bruno M, Podile Appa Rao
Abstract excerpt
The biological activities of chitosan and its oligosaccharides are greatly influenced by properties such as the degree of polymerization (DP), degree of acetylation (DA) and pattern of acetylation (PA). Here, structurally diverse chitosan oligosaccharides from chitosan polymers (DA=35% or 61%) were generated using Serratia proteamaculans wild-type chitinase D (SpChiD) and the W114A mutant which lacks...
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