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Article

Active-site mutations improved the transglycosylation activity of Stenotrophomonas maltophilia chitinase A.

Biochimica et biophysica acta. Proteins and proteomics - 1 Mar 2018

Bhuvanachandra Bhoopal, Madhuprakash Jogi, Podile Appa Rao

Abstract excerpt

Transglycosylation (TG) by family 18 chitinases is of special interest due to the many biological applications of long-chain chitooligosaccharides (CHOS). In the current study, the TG activity of chitinase A from Stenotrophomonas maltophilia (StmChiA) was improved through structure-guided mutations within and around the active site. Three independent mutants were created, targeting Trp residues from the -3 and -1...

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Identifiers

PMID: 29233759
DOI: 10.1016/j.bbapap.2017.12.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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