Article
Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.
Oncotarget - 24 Nov 2015
Jiang Yunyun, Malouf Gabriel G, Zhang Jianping, Zheng Xiaofeng, Chen Yunxin, Thompson Erika J, Weinstein John N, Yuan Ying, Spano Jean-Philippe, Broaddus Russell, Tannir Nizar M, Khayat David, Lu Karen H, Su Xiaoping
Abstract excerpt
BACKGROUND: Integrative analysis of endometrioid endometrial carcinoma (EEC) using multiple platforms has distinguished four molecular subgroups. However, the landscape of expressed long non-coding RNAs (lncRNA) and their role in charting EEC subgroups and determining clinical aggressiveness remain largely unknown. RESULTS: Using stringent criteria, we identified 1,931 expressed lncRNAs and predicted potential...
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