Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Live Imaging of LysoTracker-Labelled Phagolysosomes Tracks Diurnal Phagocytosis of Photoreceptor Outer Segment Fragments in Rat RPE Tissue Ex Vivo.

Advances in experimental medicine and biology - 1 Jan 2016

Mao Yingyu, Finnemann Silvia C

Abstract excerpt

Renewal of rod photoreceptor outer segments in the mammalian eye involves synchronized diurnal shedding after light onset of spent distal outer segment fragments (POS) linked to swift clearance of shed POS from the subretinal space by the adjacent retinal pigment epithelium (RPE). Engulfed POS phagosomes in RPE cells mature to acidified phagolysosomes, which accomplish enzymatic degradation of POS macromolecules....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Tracking
Share to Circadian Rhythm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Dyes

Share to Lysosomal-Associated Membrane Protein 1

Share to Lysosomes

Share to Phagocytosis

Share to Phagosomes

Share to Retinal Pigment Epithelium

Source

Open in PubMed Open full text

Identifiers

PMID: 26427480
DOI: 10.1007/978-3-319-17121-0_95
PMCID: PMC6788738

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Live Imaging of LysoTracker-Labelled Phagolysosomes Tracks Diurnal Phagocytosis of Photoreceptor Outer Segment Fragments in Rat RPE Tissue Ex Vivo.PMID 26427480Read ↗

Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivoSemantic proximity Read ↗

Phagocytosed photoreceptor outer segments activate mTORC1 in the retinal pigment epitheliumSemantic proximity Read ↗

Regulation of phagolysosomal activity by miR-204 critically influences structure and function of retinal pigment epithelium/retinaSemantic proximity Read ↗

The lipofuscin component A2E selectively inhibits phagolysosomal degradation of photoreceptor phospholipid by the retinal pigment epitheliumSemantic proximity Read ↗

Probing Photoreceptor Outer Segment Phagocytosis by the RPE In Vivo: Models and MethodologiesSemantic proximity Read ↗

Specialised features of melanosomes in health and disease in the retinal pigment epitheliumSemantic proximity Read ↗

Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3).Semantic proximity Read ↗

The Role of Retinal Pigment Epithelial Cells in Age-Related Macular Degeneration: Phagocytosis and AutophagySemantic proximity Read ↗

Autophagy in the retinal pigment epithelium: a new vision and future challengesSemantic proximity Read ↗

Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-derived Factor Receptor (PEDF-R)Semantic proximity Read ↗

Autofluorescent Granules of the Human Retinal Pigment Epithelium: Phenotypes, Intracellular Distribution, and Age-Related Topography.Semantic proximity Read ↗

Lysosomal Profiling with LysoTracker for Quantitative Assessment of Cellular Senescence in Human FibroblastsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.