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Article

Autofluorescent Granules of the Human Retinal Pigment Epithelium: Phenotypes, Intracellular Distribution, and Age-Related Topography.

Investigative ophthalmology & visual science - 11 May 2020

Bermond Katharina, Wobbe Christina, Tarau Ioana-Sandra, Heintzmann Rainer, Hillenkamp Jost, Curcio Christine A, Sloan Kenneth R, Ach Thomas

Abstract excerpt

Purpose: The human retinal pigment epithelium (RPE) accumulates granules significant for autofluorescence imaging. Knowledge of intracellular accumulation and distribution is limited. Using high-resolution microscopy techniques, we determined the total number of granules per cell, intracellular distribution, and changes related to retinal topography and age. Methods: RPE cells from the fovea, perifovea, and...

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Identifiers

PMID: 32433758
DOI: 10.1167/iovs.61.5.35
PMCID: PMC7405767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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