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Specialised features of melanosomes in health and disease in the retinal pigment epithelium

3 Sept 2025

Abstract excerpt

This mini-review focuses on melanosome biogenesis, positioning and function in the retinal pigment epithelium (RPE) where melanosomes absorb light scatter and protect against the harmful effects of photo-oxidation. RPE melanosomes share a common biogenesis pathway with those of skin melanocytes but are made primarily embryonically and are retained by the RPE throughout life. They do however move from the cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40970089
DOI: 10.3389/fcell.2025.1593840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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