Article
Analysis of the Molecular Evolution of the Mycobacterium Tuberculosis Drug-Resistant Gene rpoB in Asia Using a Bayesian Evolutionary Method.
Clinical laboratory - 1 Jan 2015
Xu Guangyu, Wang Jianmeng, Guo Yuqi, Bai Yu, Yuan Guangxin, An Liping, Han Xiao, Du Peige, Zhang Nan, Zheng Yan
Abstract excerpt
BACKGROUND: Tuberculosis (TB) is a serious communicable disease throughout the world. Re-emergence of the TB epidemic is aggravated by the circulation of multidrug-resistant Mycobacterium tuberculosis strains, and more than half of new cases have occurred in Asia. Therefore, it is important to understand the gene mutations underlying the development of rifampicin resistance in Asia. METHODS: In this study, we...
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