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Article

A robust distribution-free test for genetic association studies of quantitative traits.

Statistical applications in genetics and molecular biology - 1 Nov 2015

Kozlitina Julia, Schucany William R

Abstract excerpt

In association studies of quantitative traits, the association of each genetic marker with the trait of interest is typically tested using the F-test assuming an additive genetic model. In practice, the true model is rarely known, and specifying an incorrect model can lead to a loss of power. For case-control studies, the maximum of test statistics optimal for additive, dominant, and recessive models has been...

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Identifiers

PMID: 26426896
DOI: 10.1515/sagmb-2014-0050
PMCID: PMC4788466

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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