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Mutational Heterogeneity in p6 Gag Late Assembly (L) Domains in HIV-1 Subtype C Viruses from South Africa.

AIDS research and human retroviruses - 1 Jan 2016

Neogi Ujjwal, Engelbrecht Susan, Claassen Mathilda, Jacobs Graeme Brendon, van Zyl Gert, Preiser Wolfgang, Sonnerborg Anders

Abstract excerpt

Contradictory results have been reported on the impact of duplications/insertions in the HIV-1 gag-p6 late assembly domains [TSG101-binding P(T/S)APP motif and ALIX-binding LYPxnLxxL motif] heterogeneity following therapy failure. However, most studies are limited to small numbers of patients and do not include samples from South Africa, which has the largest number of HIV-1C-infected patients (HIV-1CZA). In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

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Identifiers

PMID: 26413747
DOI: 10.1089/AID.2015.0266

Genes

APP

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