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Article

C9ORF72 expression and cellular localization over mouse development

25 Sept 2015

Abstract excerpt

INTRODUCTION: A majority of familial frontotemporal lobar dementia and amyotrophic lateral sclerosis cases are associated with a large repeat expansion in a non-coding region of the C9ORF72 gene. Currently, little is known about the normal function and the expression pattern of the C9ORF72 protein. The aims of this study were to characterize the expression pattern and cellular localization of the three reported...

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PMID: 26408000
DOI: 10.1186/s40478-015-0238-7

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