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Article

Mitochondrial DNA variation in human radiation and disease.

Cell - 24 Sept 2015

Wallace Douglas C

Abstract excerpt

Environmental adaptation, predisposition to common diseases, and, potentially, speciation may all be linked through the adaptive potential of mitochondrial DNA (mtDNA) alterations of bioenergetics. This Perspective synthesizes evidence that human mtDNA variants may be adaptive or deleterious depending on environmental context and proposes that the accrual of mtDNA variation could contribute to animal speciation...

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Identifiers

PMID: 26406369
DOI: 10.1016/j.cell.2015.08.067
PMCID: PMC4743751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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