Mitochondrial genome variation and the origin of modern humans.

doi:10.1038/35047064

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Article

Mitochondrial genome variation and the origin of modern humans.

Nature - 7 Dec 2000

Ingman M, Kaessmann H, Pääbo S, Gyllensten U

Abstract excerpt

The analysis of mitochondrial DNA (mtDNA) has been a potent tool in our understanding of human evolution, owing to characteristics such as high copy number, apparent lack of recombination, high substitution rate and maternal mode of inheritance. However, almost all studies of human evolution based on mtDNA sequencing have been confined to the control region, which constitutes less than 7% of the mitochondrial...

Topics

Africa
Animals
DNA, Mitochondrial
Evolution, Molecular
Genetic Variation
Genome
Humans
Mitochondria
Molecular Sequence Data
Phylogeny
X Chromosome

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Open in PubMed

Identifiers

PMID: 11130070
DOI: 10.1038/35047064

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