Article
Preliminary testing for the Markov property of the fifteen chromatin states of the Broad Histone Track.
Bio-medical materials and engineering - 1 Jan 2015
Lee Kyung-Eun, Park Hyun-Seok
Abstract excerpt
Epigenetic computational analyses based on Markov chains can integrate dependencies between regions in the genome that are directly adjacent. In this paper, the BED files of fifteen chromatin states of the Broad Histone Track of the ENCODE project are parsed, and comparative nucleotide frequencies of regional chromatin blocks are thoroughly analyzed to detect the Markov property in them. We perform various tests...
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