Article

Markov chains improve the significance computation of overlapping genome annotations

2022-04-10

Abstract excerpt

<h4>Motivation</h4> Genome annotations are a common way to represent genomic features such as genes, regulatory elements or epigenetic modifications. The amount of overlap between two annotations is often used to ascertain if there is an underlying biological connection between them. In order to distinguish between true biological association and overlap by pure chance, a robust measure of significance is require...

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Literature Corpus work: 2967cf6a-b5a4-5b8d-b0ea-704d9718805d
DOI: 10.1101/2022.04.07.487119

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