A highly recurrent novel missense mutation in CD28 among angioimmunoblastic T-cell lymphoma patients

Abstract excerpt

Angioimmunoblastic T-cell lymphoma (AITL) is a rare, aggressive type of T-cell lymphoma (TCL) that accounts for 18.5% of mature T-cell or natural killer (NK)-cell lymphomas.[1][1] Mutations in the IDH2, TET2 , and DNMT3A genes, frequently seen in various types of cancer, have also been linked to

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