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Article

Do changes in the BDNF promoter methylation indicate the risk of alcohol relapse?

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Nov 2015

Heberlein Annemarie, Büscher Patricia, Schuster Rilana, Kleimann Alexandra, Lichtinghagen Ralf, Rhein Mathias, Kornhuber Johannes, Bleich Stefan, Frieling Helge, Hillemacher Thomas

Abstract excerpt

The neurotrophic growth factor brain derived neurotrophic factor (BDNF) was linked to the risk of alcohol relapse in clinical studies. In this study we investigated alterations in the methylation of the BDNF gene during alcohol withdrawal (day 1, 7 and 14) in 99 male alcohol-dependent patients compared to age matched healthy males (n=33). In particular, we aimed to investigate a possible association between the...

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Identifiers

PMID: 26404404
DOI: 10.1016/j.euroneuro.2015.08.018

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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