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The lncRNA BDNF-AS is an epigenetic regulator in the human amygdala in early onset alcohol use disorders

6 Feb 2019

Abstract excerpt

Adolescent alcohol drinking is known to contribute to the development and severity of alcohol use disorders (AUDs) later in adulthood. Recent studies have shown that long non-coding RNAs (lncRNAs) are critical for brain development and synaptic plasticity. One such lncRNA is natural occurring brain-derived neurotrophic factor antisense (BDNF-AS) that has been shown to regulate BDNF expression. The role of BDNF-AS...

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PMID: 30728347
DOI: 10.1038/s41398-019-0367-z

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