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Article

Effect of six type II diabetes susceptibility loci and an FTO variant on obesity in Pakistani subjects.

European journal of human genetics : EJHG - 1 Jun 2016

Shabana, Ullah Shahid Saleem, Wah Li Ka, Acharya Jayshree, Cooper Jackie A, Hasnain Shahida, Humphries Stephen E

Abstract excerpt

The aim of the current study was to analyze the effect of six type II diabetes GWAS loci rs3923113 (GRB14), rs16861329 (ST6GAL1), rs1802295 (VPS26A), rs7178572 (HMG20A), rs2028299 (AP3S2) and rs4812829 (HNF4A), and an FTO polymorphism () on obesity. The probable mechanism of action of these SNPs was analyzed by studying their association with various biochemical and anthropometric parameters. A total of...

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Share to Alpha-Ketoglutarate-Dependent Dioxygenase FTO
Share to Diabetes Mellitus, Type 2
Share to Genetic Loci
Share to Genetic Predisposition to Disease
Share to Lipids
Share to Obesity
Share to Pakistan
Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 26395551
DOI: 10.1038/ejhg.2015.212
PMCID: PMC4867451

Genes

FTO
GRB14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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