Article
rs3751812, a common variant in fat mass and obesity-associated (FTO) gene, is associated with serum high- and low-density lipoprotein cholesterol in Pakistani individuals.
Nutrition (Burbank, Los Angeles County, Calif.) - 1 Jan 2000
Qureshi Sarah Anwar, Mumtaz Amir, Shahid Saleem Ullah, Shabana N A
Abstract excerpt
OBJECTIVES: The aim of the present study was to investigate the effect of a common variant of the fat mass and obesity associated (FTO) gene, rs3751812 in obese Pakistani individuals, compare this effect with nonobese controls of the same ethnicity, and then correlate it with serum lipid profile and anthropometric parameters. METHODS: We genotyped 475 samples using TaqMan allelic discrimination assay. Serum total...
Topics
- Adult
- Alpha-Ketoglutarate-Dependent Dioxygenase FTO
- Cholesterol, HDL
- Cholesterol, LDL
- Female
- Genetic Predisposition to Disease
- Humans