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Article

SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host's NF-κB Signalling Activity.

PloS one - 1 Jan 2015

Yang Zhe, Soderholm Amelia, Lung Tania Wong Fok, Giogha Cristina, Hill Michelle M, Brown Nathaniel F, Hartland Elizabeth, Teasdale Rohan D

Abstract excerpt

Salmonella Typhimurium employs an array of type III secretion system effectors that facilitate intracellular survival and replication during infection. The Salmonella effector SseK3 was originally identified due to amino acid sequence similarity with NleB; an effector secreted by EPEC/EHEC that possesses N-acetylglucoasmine (GlcNAc) transferase activity and modifies death domain containing proteins to block...

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Source

Open in PubMed Open full text

Identifiers

PMID: 26394407
DOI: 10.1371/journal.pone.0138529
PMCID: PMC4579058

Genes

TRIM32
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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