Article
Tracing Behçet's disease origins along the Silk Road: an anthropological evolutionary genetics perspective.
Clinical and experimental rheumatology - 1 Jan 2000
Sazzini Marco, Garagnani Paolo, Sarno Stefania, De Fanti Sara, Lazzano Teresa, Yang Yao Daniele, Boattini Alessio, Pazzola Giulia, Maramotti Sally, Boiardi Luigi, Franceschi Claudio, Salvarani Carlo, Luiselli Donata
Abstract excerpt
OBJECTIVES: Behçet's disease is a multifactorial vasculitis that shows its highest prevalence in geographical areas historically involved in the Silk Road, suggesting that it might have originated somewhere along these ancient trade routes. This study aims to provide a first clue towards genetic evidence for this hypothesis by testing it via an anthropological evolutionary genetics approach. METHODS: Behçet's...
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