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Age estimation of single nucleotide polymorphisms associated with autoinflammatory diseases in anatolia: insights from ancient and modern DNA.

Human genetics - 27 Dec 2025

Karadavut Damla, Kilinc Gulsah Merve, Yet Idil

Abstract excerpt

Autoinflammatory diseases are immune system disorders that arise from abnormalities in the innate immune system. With the advent of genome sequencing, several distinct genetic loci associated with different types of autoinflammatory diseases have been identified. However, the evolutionary history of these variants, such as the age of the alleles, has not been fully explored in human populations. In this study, we...

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PMID: 41454933
DOI: 10.1007/s00439-025-02793-3

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MEFV

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