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Article

Pgc-1α and Nr4a1 Are Target Genes of Circadian Melatonin and Dopamine Release in Murine Retina.

Investigative ophthalmology & visual science - 1 Sept 2015

Kunst Stefanie, Wolloscheck Tanja, Kelleher Debra K, Wolfrum Uwe, Sargsyan S Anna, Iuvone P Michael, Baba Kenkichi, Tosini Gianluca, Spessert Rainer

Abstract excerpt

PURPOSE: The neurohormones melatonin and dopamine mediate clock-dependent/circadian regulation of inner retinal neurons and photoreceptor cells and in this way promote their functional adaptation to time of day and their survival. To fulfill this function they act on melatonin receptor type 1 (MT1 receptors) and dopamine D4 receptors (D4 receptors), respectively. The aim of the present study was to screen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26393668
DOI: 10.1167/iovs.15-17503
PMCID: PMC4585341

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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