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Article

Dialogue between E. coli free radical pathways and the mitochondria of C. elegans.

Proceedings of the National Academy of Sciences of the United States of America - 6 Oct 2015

Govindan J Amaranath, Jayamani Elamparithi, Zhang Xinrui, Mylonakis Eleftherios, Ruvkun Gary

Abstract excerpt

The microbial world presents a complex palette of opportunities and dangers to animals, which have developed surveillance and response strategies to hints of microbial intent. We show here that the mitochondrial homeostatic response pathway of the nematode Caenorhabditis elegans responds to Escherichia coli mutations that activate free radical detoxification pathways. Activation of C. elegans mitochondrial...

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Identifiers

PMID: 26392561
DOI: 10.1073/pnas.1517448112
PMCID: PMC4603447

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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